Furosemide

CATEGORIES, DRUG CLASSES, BRAND NAMES

CATEGORIES: Edema, pulmonary, adjunct; Edema, secondary to heart failure; Edema, secondary to hepatic cirrhosis; Edema, secondary to renal dysfunction; Hypertension, essential; Pregnancy Category C; WHO Formulary

Drug Classes: Antihypertensives; Diuretics

BRAND NAMES: Aldic; Aluzine; Anfuramaide; Apo-Frusemide; Apo-Furosemide; Aquarid; Aquamide; Aquasin; Arasemide; Bioretic; Cetasix; Dirine; Disemide; Diural; Diuresal; Diurin; Diurolasa; Diusemide; Diusil; Dranex; Dryptal; Durafurid; Edenol; Errolon; Eutensin; Fluidrol; Franyl; Frumex; Furmid; Frusedan; Frusema; Frusemide; Frusetic; Frusid; Furanthril; Furanturil; Furetic; Furex; Furix; Frumide; Furo-Basan; Furocot; Furodiurol; Furomen; Furomex; Furomide M.D.; Furo-Puren; Furorese; Furosan; Furosix; Furoter; Furovite; Fusid; Golan; Hissuflux; Hydrex; Hydro; Impugan; Kofuzon; Kutrix; Lasemid; Lasiletten; Lasilix; Lasix; Lasix Retard; Laxur; Liside; Marsemide; Naclex; Nadis; Nelsix; Nephron; Odemase; Odemex; Oedemex; Promedes; Promide; Radisemide; Radonna; Retep; Salinex; Salurid; Seguril; Selectofur; Trofurit; Uremide; Urenil; Uresix; Urex; Urex-M; Urian; Uridon; Yidoli; Zafurida
(Foreign Brand names outside U.S. in italics)

Tablets: Lasix is a diuretic which is an anthranilic acid derivative. Lasix for oral administration contains furosemide as the active ingredient and the following inactive ingredients: lactose, magnesium stearate, starch, and talc. Chemically, it is 4-chloro-N-furfuryl-5-sulfamoylanthranilic acid. Furosemide is available as white tablets for oral administration in dosage strengths of 20, 40 and 80 mg.

Furosemide is a white to off-white odorless crystalline powder. It is practically insoluble in water, sparingly soluble in alcohol, freely soluble in dilute alkali solutions and insoluble in dilute acids.

The CAS Registry Number is 54-31-9.

Injection: Lasix injection is composed of 4-chloro-N-furfuryl-5- sulfamoylanthranilic acid, sodium chloride for isotonicity and sodium hydroxide to adjust pH.

Lasix injection 10 mg/ml is a sterile, non-pyrogenic solution in ampules, disposable syringes and single dose vials for intravenous and intramuscular injection.

Oral Solution: Lasix oral solution contains furosemide as the active ingredient and the following inactive ingredients: alcohol 11.5%, D&C yellow #10, FD&C yellow #6 as color additives, flavors, glycerin, parabens, purified water, sorbitol; sodium hydroxide added to adjust pH. Lasix oral solution 10 mg/ml is an orange flavored liquid for oral administration.